The young researchers of BioMolStruct study biomolecules and biomolecular complexes playing essential roles in cellular signaling and metabolism, with a focus on proteins, protein complexes, and lipid/protein interactions that are linked to ageing, cancer, neurodegenerative, metabolic, and cardiovascular diseases as well as genetic disorders. Our research program aims to understand structure, conformational dynamics, and detailed function of these systems and their modulation by drug-like compounds.
Our international program is highly attractive for students in biomedical sciences who seek an intellectually demanding – and rewarding – PhD training to pursue a career in academia or industry. We prepare our BioMolStruct young researchers to master future challenges in the fields of biomedical research with profound knowledge and innovative approaches
Life on the scale of biological molecules is a mesmerizing interplay of well-defined structures and highly dynamic motions challenging today’s researchers to understand the molecular details of biology. This intrinsic complexity provides unique opportunities, which we aim to address in our educational program. Structural biology plays a central role in biomedical research. It has helped to decipher fundamental macromolecular structures that underlie (patho)physiological processes. The last few years have led to a paradigm shift in the field from delineating biological functions from static structures only, to the need to include molecular dynamics for a comprehensive understanding of the underlying mechanisms.
